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The diverse and emerging scientific evidence presented in this concise yet well-documented volume (>350 references) explores the numerous links between prenatal fluoride exposure and adverse health consequences for mother and child – compelling reasons why mothers-to-be should not drink fluoridated tap water and beverages produced with it. 108 pages • 5.25 x 8" • $13.00 Updated in 2020 Available on Amazon whose "Read sample" feature is set to show the maximum number of pages allowed. Contents INTRODUCTION 1) FLUORIDE, PREMATURE BIRTH AND IMPAIRED NEURODEVELOPMENT A global review of recent laboratory, clinical, and ecological evidence that fluoride is a significant risk factor for premature birth and long-term neurological disabilities in children. Updated and revised since published in the November 2013 Townsend Letter: The Examiner of Alternative Medicine. Sections Prenatal Brain Development US Preterm Birth Rate Unusually High Residence in the US a Risk Factor for Preterm Birth Best-Available Science Will Reduce Preterm Birth by Only 5% Fluoride: Ancient Enemy of Biological Systems Molecular Mechanisms of Fluoride Toxicity Fluoride Inhibits the Enzyme Enolase Fluoride, Anemia, and Preterm Birth: A.K. Susheela's Research Prenatal Fluoride Linked to Low Birthweight Low Birthweight, Cognitive Problems, Autism, and Obesity Iron-Deficiency Anemia Microflora in the GI Tract Thyroid Disorders and Preterm Birth Prematurity and Infant Mortality Water Fluoridation and Preterm Birth Rates Link Between Preterm Birth and Brain Disorders HPA Axis and the Gut Attention-Deficit Hyperactivity Disorder (ADHD) Prenatal Fluoride and Hyperactivity Fluoride, Defective Tooth Enamel, and Prematurity Genetic Factors Fluoride Contaminates US Processed Food & Beverage Chain Cognitive Scores and Gestational Age 94 References 2) PLACENTAL FLUOROSIS: FLUORIDE AND PREECLAMPSIA New research and diverse evidence implicate fluoride and fluorosis in the pathogenesis of preeclampsia, the dangerous pregnancy complication caused by the abnormal placenta. Updated and revised since published in the May 2015 Townsend Letter. Sections ER Stress – Link Between Fluorosis and Preeclampsia Fluoride Causes ER Stress in in Dental and Skeletal Fluorosis ER Stress in Preeclampsia Fluoride: Hypertension, Arterial Stiffness, and Preeclampsia Fluoride and Calcification in Arteries and the Pineal Gland Fluoride, Oxidative Stress, and Placental Melatonin Acetaminophen and Fluoride – Synergistic Damage Angiogenic Factors and Fluoride Inflammation: Periodontitis, Preeclampsia, and Dental Fluorosis Preeclampsia Increases Risk of Autism and Preterm Birth Fluoridated Water, Dental Fluorosis, and Preeclampsia Fluoridated Water, Hypothyroidism, and Preeclampsia FDA: Fluoride and Pregnancy Research Needed Preventing Preeclampsia 77 References 3) PRENATAL FLUORIDE AND AUTISM Fluoride swallowed in amniotic fluid may disrupt colonization and composition of bacteria in the fetal GI tract – adversely affecting neurological and immunological development. Updated and revised since published in the April 2016 Townsend Letter. Sections Fluoride Weakens Bacterial Adhesion Forces Adhesion Forces and Bacterial Colonization of the GI Tract Fluoridated Amniotic Fluid Altered Microbiome in Autism Spectrum Disorder Gut Bacteria, Immune System, Autism, and Fluoride Adhesion Molecules, Autism, and Fluoride Fluoride Adversely Affects Synaptic Development Fluoride is a "Developmental Neurotoxicant" When a Pregnant Woman Consumes Fluoride, So Does Her Baby Tolerable Upper Intake Level of Fluoride Poison Warning on Fluoride Toothpaste Developmental Defects Increase with Fluoride Levels in Water Genetic Susceptibility to Fluoride's Adverse Effects Fluorinated Pharmaceuticals in Pregnancy and Autism SSRIs, Preeclampsia and Autism Prenatal Fluoride, Preterm Birth, and Autism Fluoridated Water: Hypothyroidism, Autism, and ADHD More Fluoride Absorbed from Artificially Fluoridated Water Fluoride, Copper, and Autism Spectrum Disorder Prenatal Fluoride: All Risk and No Benefit Lack of Fluoride-Pregnancy Research Health of Maternal Microbiome Determines Autism Risk "The Prenatal Microbiome: A New Player for Human Health" 120 References 4) FLUORIDE AND MENTAL DECAY: CAUSATION & CORRELATION Back in the stone age of neuroscience, a controversial public health intervention was implemented. In 1945, because of its ecological association with decreased dental decay, fluoride was added to US drinking water. Now, fluoridation must end because of its many causative biochemical links to increased mental decay. Published in the October 2019 Townsend Letter. Sections Fluoride's Causative Biochemical Links    Arterial Stiffness    Endothelial Dysfunction    ER Stress    Microglial Activation Fluoridation's Ecological Correlations    Alzheimer's Disease    Hypertension and Stroke    Kidney Disease    Attention-Deficit Hyperactivity Disorder (ADHD)    Mental Retardation/Intellectual Disability    Preterm Birth 49 References (16 studies from 2018 & 2019; only 2 from the 1900s) Decayed and Missing Years EPA's List of "Developmental Neurotoxicants" Includes Fluoride Appendices      A. Unborn Babies are Overexposed to Fluoride in Tap Water      B. Fluoride Research Needed: National Research Council      C. Fluoridation Chemicals Leach Lead into Drinking Water      D. Why We Should Not Believe the Fluoridation Sales Pitch "For those who have felt squeamish about resisting the pro-fluoride lobby, MacArthur's article cites numerous studies showing the relationship between fluoride bioaccumulation and adverse effects on human health. MacArthur's previous articles in the Townsend Letter and this article will serve well when supporting antifluoridation efforts." – Jonathan Collin, MD Publisher "Researcher and citizen advocate John MacArthur – who has written several times before about the mischief caused by fluoride – writes in the October 2019 Townsend Letter about the devilry achieved by fluoride on the brain and its cellular functioning... "MacArthur examines the evidence of how the fluoride that we absorb from our toothpaste and, without consent, from our drinking water insults our brain cells and the blood brain barrier and the synaptic proteins that enable neuron communication. When you compare states that have the largest number of fluoridating cities to those that have the least, there is more neurological disease in the states that are heavy fluoridators. This includes that great scourge befuddling researchers and doctors, Alzheimer's disease. Shouldn't that be a reason to give the fluoridating stalwarts pause? Maybe a reason for the FDA to investigate? And if Alzheimer's isn't your thing, MacArthur's examination of the statistics shows a similar picture of increased death from hypertension, stroke, and kidney disease in states that push fluoridation versus those that don't." – Jonathan Collin, MD Publisher (October 2019) Previous back-cover illustration: courtesy of Sheng Yi Lee (©2015)